Abstract

Commentary: Activation of Pedunculopontine Glutamate Neurons Is Reinforcing.

Highlights

  • Edited by: Nuno Sousa, Instituto de Pesquisa em Ciências da Vida e da Saúde (ICVS), Portugal

  • We focus on the recent findings from Yoo et al (2017), who implemented optogenetic method as a strong and trending tool for detection of specific circuits and cell dominancy of the Ventral Tegmental Area (VTA) reward pathway

  • By cell-type selective approaches, they claim that glutamatergic projections of the pedunculopontine tegmental nucleus (PPTg) neurons to VTA, are the most important neural substrate of positive reinforcement among heterogonous population of dopaminergic, glutamatergic and GABAergic neurons of VTA

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Summary

Introduction

Edited by: Nuno Sousa, Instituto de Pesquisa em Ciências da Vida e da Saúde (ICVS), Portugal. A commentary on Activation of Pedunculopontine Glutamate Neurons Is Reinforcing by Yoo, J. By cell-type selective approaches, they claim that glutamatergic projections of the pedunculopontine tegmental nucleus (PPTg) neurons to VTA, are the most important neural substrate of positive reinforcement among heterogonous population of dopaminergic, glutamatergic and GABAergic neurons of VTA.

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