Comment: Revisiting Lassen cerebral blood flow constancy with hysteresis and 3D.

Abstract

Roh et al.1 present a unique case of severe, prolonged hypercapnic respiratory failure that triggered refractory global cerebral edema (GCE). This case report is interesting because edema was not abatable by hyperventilation, despite adequate reversal to a normocapnic state, and responded only to aggressive osmotherapy. The authors thank Julie D. Coats, medical illustrator, for her assistance in graphic design.