Abstract
We have read with great interest the article published by Samaras et al. (1); the authors found an association of metformin use with slowed cognitive decline and lower risk of incident dementia in older adults with type 2 diabetes. In this work, the authors reported an impressive 81% risk reduction in the incidence of dementia between patients with diabetes and metformin (DM+MF) compared with the group with diabetes without metformin (DM-noMF). We found some aspects of the study worth further discussion. First, there is high contrast …
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