Abstract

In the introduction of the article “Reproducibility of Cerebrospinal Venous Blood Flow and Vessel Anatomy with the Use of Phase Contrast–Vastly Undersampled Isotropic Projection Reconstruction and Contrast-Enhanced MRA,”[1][1] the authors pointed out that the Zamboni hypothesis, known as

Highlights

  • In the introduction of the article “Reproducibility of Cerebrospinal Venous Blood Flow and Vessel Anatomy with the Use of Phase Contrast–Vastly Undersampled Isotropic Projection Reconstruction and Contrast-Enhanced MRA,”[1] the authors pointed out that the Zamboni hypothesis, known as chronic cerebrospinal venous insufficiency (CCSVI), “has prompted much interest in the accuracy and reproducibility of cerebrospinal venous flow measurements, which have not yet been established.” The authors stated that the diagnosis of CCSVI based on duplex ultrasonography (US) has well-known limitations that can be overcome by using the MR imaging technique

  • We agree with the authors about the need to investigate the cerebrospinal flow measurements, and we believe that MR imaging is a promising technique for this task

  • The US technique is safe, allows real-time visualization of the moving structures, and is relatively inexpensive compared with MR imaging

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Summary

Introduction

In the introduction of the article “Reproducibility of Cerebrospinal Venous Blood Flow and Vessel Anatomy with the Use of Phase Contrast–Vastly Undersampled Isotropic Projection Reconstruction and Contrast-Enhanced MRA,”[1] the authors pointed out that the Zamboni hypothesis, known as chronic cerebrospinal venous insufficiency (CCSVI), “has prompted much interest in the accuracy and reproducibility of cerebrospinal venous flow measurements, which have not yet been established.” The authors stated that the diagnosis of CCSVI based on duplex (gray-scale and color Doppler) ultrasonography (US) has well-known limitations that can be overcome by using the MR imaging technique. We agree with the authors about the need to investigate the cerebrospinal flow measurements, and we believe that MR imaging is a promising technique for this task.

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Conclusion
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