Abstract
Type 1 diabetes (T1D) is an important risk factor for development of chronic kidney disease (CKD) and cardiovascular disease (CVD). Earlier detection of risk factors for diabetic complications can improve the risk stratification of the patients with diabetes and allow targeted treatment. Recently, Pilemann-Lyberg et al. (1) reported that a higher uric acid (UA) level is associated with a higher risk of CKD and CVD. Importantly, adding UA to the adjusted model including conventional risk factors can significantly improve the relative integrated discrimination index. This study was interesting and provided further support that UA should be regarded as a risk factor of CKD and CVD in T1D. Epidemiologic studies have shown inconsistent conclusions about …
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