Abstract

The close relationship between the endocrine system and neuropsychiatric functions is becoming more and more recognized. The evidence pointing to this interrelation has been accumulating from many sources. Thus, anatomical (1), biochemical (2), psychological (3), neuropathological (4) and clinical studies (5–7) have all played a part. The observation by Rowe (8) that approximately 75 per cent of 374 problem children disclosed definite evidence of pituitary defect represents one of the most exhaustive clinical studies bearing upon the problem. The frequent occurrence of endocrinopathy and misbehavior in children may indicate that a common genetic factor is responsible for both the physical and mental aberrations. Personal observation, however, has led to the impression that the problem behavior of many endocrinopathic children like the misbehavior of the normally constituted child is frequently experientiallydetermined. Such a child, because of his somatic disfigurement becomes the target of jibings and ex...

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