Abstract

Combined use of intracervical foley catheter and vaginal misoprostol for termination of second trimester pregnancy: a three-year observational study

Highlights

  • Second trimester abortions constitute 10–15% of all induced abortions worldwide but are responsible for two-thirds of all major abortion-related complications [1]

  • The induction to abortion interval was 8.16 ± 1.52 hours in the combined group compared to 12.76 ± 1.63 hours in the misoprostol group (P value

  • The combination of intravaginal misoprostol and intracervical Foley catheter for second trimester pregnancy termination has been described in two previous studies with conflicting results [8,9]

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Summary

Introduction

Second trimester abortions constitute 10–15% of all induced abortions worldwide but are responsible for two-thirds of all major abortion-related complications [1]. The most efficacious regimen for medical second trimester termination of pregnancy appears to be the use of a combination of mifepristone, followed by misoprostol [3,4,5]. This regimen has had 97–99% rate of abortion within 24 hours [3,6]. The combination of intravaginal misoprostol and intracervical Foley catheter for second trimester pregnancy termination has been described in two previous studies with conflicting results [8,9]. The aim of this study was to assess the effectiveness, safety and acceptability of intracervical Foley catheter and vaginal misoprostol versus vaginal misoprostol for termination of second trimester pregnancy

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