Abstract
A study was undertaken to determine whether measurements of radiological indices from chest X-rays and body mass index (BMI) were useful in predicting pulmonary artery hypertension. Measurements of the cardiothoracic ratio (CTR) as well as right descending pulmonary artery diameter (RDPA) and BMI were made in 27 patients with chronic obstructive pulmonary disease (COPD). Mean pulmonary arterial pressure (mPA) correlated with CTR, RDPA and BMI. Multiple regression analysis gave the useful equation: predicted mPA = -3.523 + 0.196xBMI + 0.110xCTR + 0.786xRDPA (r = 0.704, p < 0.002). Fifteen patients were found to have pulmonary hypertension, defined as mPA > or = 20 mmHg. The sensitivity of CTR and BMI were 86.7%. The specificity of BMI was 83.3%. These results suggest that the measurements CTR, RDPA and BMI may be useful in screening for pulmonary hypertension in patients with COPD.
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