Abstract
The use of drugs in the treatment of patients with renal failure requires a knowledge of excretion, biotransformation and pharmacologic activity of metabolites. Narcotics, analgesics, psychotherapeutic agents, drugs affecting the heart and circulation, various sorbents, resins and gels, anabolic hormones and nutritional supplements are among the more frequently used drugs for patients with end-stage renal disease. Indications and dosages of these drugs must be modified for patients with renal failure, and mechanisms of their biotransformation must be studied. This combined seminar presents the participants' studies and analyses of the problems surrounding the use of these various pharmacologic agents.
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