Abstract

Introduction and importancePrecision Medicine and evidence-based clinical treatment approach are proposed worldwide in medical science nowadays. Orthodontic first approach (OFA) and Computer-aided surgical simulation (CASS) combined 3D-printing technique offered more chances for the doctors to obey the principle of Precision Medicine in the orthodontic and orthognathic approach. Case presentationWe reported a 20-year-old patient, with skeletal Class III relationship and asymmetric mandible, was treated by OFA. And with the CASS combined 3D-Printing Technique, the presurgery simulation and 3D-printed surgery guiding splint and stable splint offered the Combined Orthodontic and Orthognathic Treatment (COOT) a powerful and accurate guiding. The results exhibited that the patient had a perfect maxilla and mandible relationship and significant improvement in profile. Clinical discussionThere is still a debate between “surgery first” (SF) and conventional OFA. In this study, we analyzed the trend of different approaches in the COOT, which was a team work and required mainly the collaboration of orthodontist and Orthognathic surgeon. This study showed the precision of the CASS could offer for the OFA to evoke people immersing in saving time in COOT. ConclusionAll of these indicated that CASS was a powerful and precise method for COOT, which could offer the patient an esthetic and stable result.

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