Abstract
Objective We present an automated scheme to correct PET max-uptake-values of small to medium-sized pulmonary nodules for motion blur and partial volume averaging. Both effects cause significant underestimation of PET max-uptake-values, particularly in nodules below 25 mm diameter, but nodules up to 75 mm might be affected. This compromises the power of PET for the differential diagnosis of such nodules, in particular benign versus malignant. Thus, correcting PET max-uptake-values has the potential to improve the classification of PET-positive pulmonary nodules.
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