Abstract

Conventional rectilinear liver scanning using labelled colloid taken up by hepatic reticuloendothelial cells demonstrates space occupying lesions as “cold” areas and cirrhosis as “patchy” uptake. Intravenous rose bengal (tetraiodotetrachlorfluorescein) which is cleared by hepatic parenchymal cells and passes via the biliary system into the gut, usually gives similar appearances to the colloid scan. In a patient with alcoholic cirrhosis and a hepatoma there was a marked regional difference in the distribution of these scanning agents within the liver, and the hepatoma concentrated rose bengal. W.M., a 60-year-old woman, presented with six months' increasing abdominal distension. Ten years previously she had been investigated in the United States with similar symptoms and a clinical diagnosis of cirrhosis was made. The patient admitted to a heavy alcohol intake for many years.

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