Abstract
Twenty-four-hour ambulatory recording of esophageal pH and pressure is a newly developed technique that has the potential of proving that a patient's noncardiac chest pain is of esophageal origin (esophageal reflux or motor abnormality). Until now four groups described their experiences with application of the technique in the work-up of noncardiac chest pain. It is now clear that the diagnostic yield of the technique in this syndrome is rather limited, especially when the incidence of pain episodes is low. Reflux appears to be a more common cause of chest pain than esophageal motor disorders. Complete quantitative analysis of the 24-hr motility data by hand is very time-consuming, so that automated, computerized data analysis is a prerequisite for more widespread clinical use of the technique.
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