Abstract
54 patients 42-65 years old with uncomplicated hypertension (stage 2) were studied. The 24-hour blood pressure (ВР) monitoring and doppler-echocardiograpy were performed at baseline and after 16 weeks of treatment. Patients were randomized into 2 groups. In the 1st group patients received combination indapamide with verapamil retard, and in 2nd group, combination of indapamide with amlodipine. The circadian rhythm of BP profile was normalized in 83,9 % of patients in 1st group and in 78,6 % of patients in the 2nd group. In the 1st group, the combination therapy is more effective in patients with diastolic left ventricular dysfunction (DDLV) type I, non-dipper profile of circadian rhythm of BP, and with a hyperkinetic type of circulation. In the 2nd group, combination therapy was effective in patients with DDLV type 2-3 and with a hypokinetic type of circulation.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: "Arterial’naya Gipertenziya" ("Arterial Hypertension")
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
