Abstract
Combination of thymosin α1 with conventional therapy improves APC and IL-1R1 levels in children with severe pneumonia
Highlights
Pneumonia is a common disease that endangers human health, and its death rate ranks first on the list of infectious diseases, accounting for onefifth of all deaths caused by diseases worldwide [1]
A total of 96 children with severe pneumonia over a period of two years were used for this study, and they consisted of 46 males and 50 females within the age range of 0.1 - 6 years
Patients in the control group were placed on conventional treatment programs such as antibacterial, cough, electrolyte balance, Trop J Pharm Res, October 2018; 17(10):2094 nutritional support and oxygen therapies, while those in the observation group in addition to the conventional treatment received thymosin α1 treatment twice daily for the first 3 days, once daily until the 7th day, after which the adverse reactions were observed and treated
Summary
Pneumonia is a common disease that endangers human health, and its death rate ranks first on the list of infectious diseases, accounting for onefifth of all deaths caused by diseases worldwide [1]. A total of 96 children with severe pneumonia over a period of two years were used for this study, and they consisted of 46 males and 50 females within the age range of 0.1 - 6 years (mean age = 3.0 ± 1.2 years, and mean duration = 13.4 ± 2.2 days). Their acute physiology and chronic health evaluation II (APACHE II) was 20.3 ± 3.2 points. Patients in the control group were placed on conventional treatment programs such as antibacterial, cough, electrolyte balance, Trop J Pharm Res, October 2018; 17(10):2094 nutritional support and oxygen therapies, while those in the observation group in addition to the conventional treatment received thymosin α1 treatment (subcutaneous injection of thymosin α1 at a dose of 1.5 mg per injection) twice daily for the first 3 days, once daily until the 7th day, after which the adverse reactions were observed and treated
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