Abstract

Triple-negative breast cancer (TNBC) is a specific subtype, the most lethal and with the worst prognosis, and is prone to develop drug resistance during advanced chemotherapy. The combined application of radiotherapy and immunotherapy has gradually entered the public eye. The PD-L1 / PD-1 immune checkpoint inhibitors can enhance the local effect of radiotherapy and relieve the immunosuppressive effect in tumor patients, and the up-regulation of PD-L1 expression caused by radiotherapy also helps the checkpoint inhibitors to play a stronger effect. More patients with TNBC can gain a higher benefit from this.

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