Abstract
Combination of local Botulinum toxin A injections and standard oral drug treatment allows improvement of long-term pain management in severe post-herpetic neuralgia: A case report
Highlights
Post-herpetic Neuralgia (PHN) is a very painful neuropathic status as the consequence of nerve injuries (e. g. demyelinisation, loss of axon, small-fiber-degeneration, reorganization in dorsal horn, neuroplastic central changes) due to herpes-zoster-infection
Systematic reviews showed that Botulinum toxin A (BoTN A) may be helpful in controlling neuropathic pain like in Post-herpetic Neuralgia (PHN)
We introduce a case report on the effects of a long-term management with intracutaneous BoTN A injections combined with classic drug treatment in a patient with severe PHN
Summary
PHN is a very painful neuropathic status as the consequence of nerve injuries (e. g. demyelinisation, loss of axon, small-fiber-degeneration, reorganization in dorsal horn, neuroplastic central changes) due to herpes-zoster-infection. We introduce a case report on the effects of a long-term management with intracutaneous BoTN A injections combined with classic drug treatment in a patient with severe PHN. The combination of regular BoTN A therapy every three month and oral drug treatment allows to reduce pain rating with VAS by 50% and suggested that this combination may be helpful for long term management of severe PHN.
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