Combination of increased situational anxiety and endothelial dysfunction in young athletes as a condition for microcirculation spasm: assessment methods and correction using a specialized honey bar-candy

Abstract

Objective: study of psychoemotional-volitional sphere and endothelium-dependent factors of cardiovascular risk, the level of performance and recovery time in athletes before and after a 2-month intake of a specialized athlete’s nutrition product (SANP) honey bar-candy “Gold F25 ApiSpeis Light”.Materials and methods: the main group of 58 athletes (under the age of 18) used SANP for 2 months. Control group-1 included 32 schoolchildren and students, not athletes, to assess the age limits of endothelium-dependent vasodilation, blood composition and the presence of risk factors for atherosclerosis in young athletes. The control group-2 included 30 young athletes under 18 years old without the use of SANP to compare the indicators in the main group before and after taking the honey bar. The psycho-emotional sphere was studied using the Spielberger-Hanin scale of anxiety and WAM testing: Well-being, Activity and Mood. In addition, the maximum achieved load, maximum oxygen consumption, time to reach the threshold of anaerobic metabolism, systolic blood pressure, heart rate, neurovegetative stress index and recovery time after exercise were determined. Also, tests with reactive hyperemia (TRH) and hyperventilation (TGV) on the brachial artery were performed to assess endothelium-dependent vasodilation and vasoconstriction, conjunctival biomicroscopy on a slit lamp with calibrometry of arterioles and venules, general and biochemical blood tests.Results: the normalization of situational anxiety, psychoemotional stress and hyperfunction of the sympathoadrenal system was established. There was a decrease in the levels of cortisol, neurovegetative stress index, improvement of well-being, activity and mood against the background of elimination of endothelial dysfunction, improved performance and reduced recovery time after work. The analysis of multiple canonical correlations revealed a close relationship between the psychoemotional state, endothelial dysfunction and microcirculation spasm (R = 0.86; p < 0.0001).Conclusion: it has been proven that a combination of increased situational anxiety, neurovegetative overexertion, hyperfunction of the sympathoadrenal system and endothelial dysfunction can form a spastic type of peripheral circulation and provoke the onset of arterial hypertension. It was found that the course intake of honey ingot has anti-stress, antioxidant, erythropoietic, vasodilating and antispastic effects, improves performance and recovery after stress. Ingot “Gold F25 ApiSpeis Light” is included in the FMBA Formulary as a specialized product for the nutrition of young athletes of the Russian national teams.