Abstract
In December 2019, novel coronavirus pneumonia-19 (COVID-19) was discovered in the viral pneumonia cases that occurred in Wuhan, China, and then quickly spread around the world. This report described the clinical course of two COVID-19 patients and the purpose of the study was to discuss the combination of chest CT and clinical features for diagnosis of COVID-19. The first case was a typical COVID-19 case. A 66-year-old female presented to our hospital with a 3-day history of fever. She had contact with a COVID-19 patient. Chest CT showed a typical COVID-19 appearance. She was diagnosed with COVID-19 by a positive nucleic acid test. The second case was a 50-year-old male with a 2-day history of fever. He denied having been to Wuhan. Chest CT also showed typical features of COVID-19 pneumonia. COVID-19 nucleic acid tests were repeated up to seven times and the results remained controversial. Eventually, he was diagnosed with COVID-19. Our study shows that chest CT has high sensitivity for diagnosis of COVID-19 in clinical practice, particularly when the nucleic acid test is negative. The chest CT should be considered as a diagnostic tool for the COVID-19 screening, comprehensive evaluation, and follow-up and patients would benefit from effective treatments in time.
Highlights
In December 2019, a succession of pneumonia cases, which were later proven to be caused by a novel coronavirus, emerged in Wuhan City, Hubei Province, China
In December 2019, novel coronavirus pneumonia-19 (COVID-19) was discovered in the viral pneumonia cases that occurred in Wuhan, China, and quickly spread around the world
This report described the clinical course of two COVID-19 patients and the purpose of the study was to discuss the combination of chest computed tomography (CT) and clinical features for diagnosis of COVID-19
Summary
In December 2019, a succession of pneumonia cases, which were later proven to be caused by a novel coronavirus (named as novel coronavirus pneumonia19 [COVID-19] by the World Health Organization [WHO] on January 12, 2020), emerged in Wuhan City, Hubei Province, China. COVID-19 had quickly spread inside of Hubei Province, throughout China and other countries. As of March 23, 2020, a total of 3,49,828 COVID-19 cases had been reported in at least 172 countries. A total of 15,336 patients have died of COVID-19. Chest computed tomography (CT) is used for diagnosis of COVID-19, as an important complement to the reverse-transcription polymerase chain reaction (RTPCR) tests [4]. We reported two cases and the purpose of the study was to discuss the combination of chest CT and clinical features for diagnosis of COVID-19
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