Abstract

Background: Pseudomyxoma peritonei (PMP), is a rare cancer of the peritoneum. Primary tumor, as it develops in the lumen of the appendix, would clog the appendix and lead to an accumulation of mucus, which would lead to the rupture of the appendix in the peritoneum cavity. This origin then raises the hypothesis of a bacterial component associated with tumor cells. In addition, many vessels are found in this disease. These two components have led our unit to explore the effect of antibiotics and anti-angiogenic combination drugs on the development of PMP.

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