Abstract
To analyze the impact of the initial vision and surgical time for endoscopic transnasal/transethmosphenoid optic canal decompression (ETOCD) in the treatment of indirect traumatic optic neuropathy (TON). This retrospective case series analysis included 72 patients with indirect TON who underwent ETOCD from August 2017 to May 2019. Visual acuity (VA) was compared before and after surgery to estimate the improvement rate. The overall VA improvement rate of ETOCD was 54.2%. There were 83.3% and 33.3% improvement rate ofpatients with residual vision and blindness, respectively. VA was improved in 60.9% of patients treated within 3days, 61.5% treated within 7days, and 35.0% treated later than 7days. Of the blindness patients, 50.0%, 37.5%, and 0.0% were treated within 3days, 3-7days, and later than 7days, respectively. Of patients with residual vision, 85.7%, 92.3%, and 70.0% were treated within 3days, 3-7days, and later than 7days, respectively. A statistically significant difference was found between patients with residual vision and those with blindness (P < 0.01), as well as between patients who received ETOCD within 7days and those who received ETOCD later than 7days (P = 0.043). The improvement rate of blindness patients managed within 3days (P = 0.008) and 3-7days (P = 0.035) was significantly higher than that for patients managed beyond 7days. Indirect TON patients can directly benefit from ETOCD, and patients with residual vision have better improvement rates. ETOCD should be performed as soon as possible to salvage the patient's VA, especially within the first 7days. For blindness patients, it is necessary to carry out the surgery within 7days with increased benefit seen before 3days.
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