Abstract
Senaka William Bibile was born on the 13th of February 1920 at Atadagewatta Walawwa. His parents were Mr. Charles William Bibile, the “Rate mahatttaya” of Bibile and Mrs. Sylvia Augusta Ubayasekera. Prof Bibile had his primary and secondary education at Trinity College, Kandy. He graduated from University of Colombo with first class honours obtaining distinctions and gold medals in Medicine and Surgery. He obtained his Ph.D. from the University of Edinburgh and on his return to Sri Lanka, was appointed the Professor of Pharmacology. He was the first Dean of the Faculty of Medicine at Peradeniya from 1967 to 1970. Prof Bibile was also instrumental in initiating the idea of building the Peradeniya Teaching Hospital.
Highlights
The topic of this oration is on obesity, a condition where the use of drugs has a minimal role to play
Individuals who are on renin angiotensin (RAS) blockers such as ACE inhibitors or Angiotensin receptor blockers have a lower incidence of Type-2 diabetes[15]. This led us to hypothesize that over-activation of the adipose tissue RAS is a link between obesity, insulin resistance and metabolic syndrome
We have previously shown that children participating in a creative after school program exhibit overall healthier lifestyle practices compared to the average pediatric population in USA
Summary
Obesity is a condition of abnormal or excessive fat accumulation that may impair health. When the body has surplus energy from excessive food intake, it is converted to fat and stored in a specialized tissue called the “adipose tissue” This tissue is mainly present underneath the skin, while it is located inside the abdomen around internal organs of the body. The risk of dying from cardiovascular disease increases with a BMI of greater than 25, and this risk is further increased with a BMI of over 30 That is how these BMI cutoffs were decided. Measures of more than or equal to 90 and 80 cm are considered to be the cutoffs for abdominal obesity for Asian males and females respectively. Obesity is associated with metabolic syndrome, which increases the risk for type-2 diabetes and cardiovascular disease. While obesity is associated with these chronic illnesses, there is emerging evidence that it is obesity which causes most of these conditions
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