Abstract

chronic post-traumatic stress disorder (PTSD) is commonly accompanied by depression and anxiety as comorbidity. The psychological states, such as depression and anxiety, can increase pain symptoms. A number of recent research results have shown that chronic post-traumatic stress disorder and chronic pain frequently co-occur and similar mechanisms have been identified that sustain both conditions. Method: the data were collected from medical records of 184 Croatian war veterans diagnosed with chronic PTSD and chronic pain as co-morbid condition. On the basis of medical records, interviews and different types of self-assessment questionnaires the inter-relationship between chronic pain and chronic PTSD was analysed. PTSD was assessed by CAPS (Clinical Administered Posttraumatic Scale) and M-PTSD (Mississippi Scale for combat PTSD), whereas pain was measured by Melzack-McGill Pain Questionnaire—short form (MPQ-SF) and Visual Analogue Scale (VAS). Results: the combat veterans with PTSD reported in descending order the following: pain in the head, back pain, widespread pain and limb pain. The patients with chronic PTSD had significantly higher total pain scores as well as affective and sensory pain components when compared to the patients without PTSD. Anxiety and depression were also highly correlated with pain. The relation between pain severity and depression was mediated by the severity of PTSD. Conclusion: our findings are directed towards the need for multidisciplinary approach in the treatment of patients with chronic PTSD and co-morbid chronic pain, which will optimize treatment and result in more cost-effective care.

Highlights

  • Posttraumatic stress disorder (PTSD) includes psychological imbalance and neurophysiologic dysfunctions resulting in behaviour changes that significantly affect the relation between an individual and his social and natural environment

  • Our study results have shown a significant degree of PTSD symptoms to persist in war veterans despite long-term treatment

  • The relation has been confirmed between the tests used for the assessment of PTSD, anxiety, depression and sensory and affective components of pain, leading to the conclusion that there is statistically significant correlation between all the applied tests

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Summary

Introduction

Posttraumatic stress disorder (PTSD) includes psychological imbalance and neurophysiologic dysfunctions resulting in behaviour changes that significantly affect the relation between an individual and his social and natural environment. Similar to chronic PTSD, there is an increasing evidence indicating the patient’s hereditary predisposition to the development of chronic pain, which, following the continuing and strong nociceptive stimuli from the periphery resulting in neuroplastic changes in the basal ganglia and the cortex, can serve as a model for the development of chronic posttraumatic stress disorder. The most recent studies have shown that pain is one of the most common symptoms in PTSD patients, regardless of the nature of traumatic experience. The PTSD patients showed higher levels of chronic pain, much more intense chronic pain, and greater number of painful regions in the body than the control study group.

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