Abstract

Ageing is a conserved phenomenon across all species and imposes an ever-increasing risk of dysfunction and death in older organisms.Growing evidences have shown that sirtuins are essential factors those delay cellular senescence and extends the organismal lifespan through the regulation of diverse cellular processes, this needs food rich in antioxidants and polyphenols to activate sirtuin Aging is beautiful. Every wrinkle, crinkle and spot is hard-earned proof of a life well lived. But just because you’ve earned your stripes or the lines on your face, it doesn’t mean you don’t want to look your very best. The truth is, you can love your age and yourself and still want to know how to look younger and live disease free life, One of the most promising targets for anti-ageing approaches are proteins belonging to the sirtuin family.

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