Abstract

Hemoglobin components of human embryonic red blood cells obtained from intact embryos of 20 and 40 mm crown-rump length could be separated by column chromatography on DEAE-Sephacel. The isolation of Hb Gower 1, Hb Gower 2, Hb Portland, Hb F, Hb F1, and Hb A is possible by this method. In the smaller embryos with only 30% of fetal hemoglobin Hb Gower 1 is the predominant component, whereas in the larger ones with 61% of fetal hemoglobin more Hb Gower 2 than Hb Gower 1 is found.

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