Abstract
The complex composed of alizarin complexone (ALC) and Ni2+ has been developed as a colorimetric probe for the selective recognition of histamine over other neurotransmitters in an aqueous solution via the indicator displacement approach. ALC formed a complex with Ni2+ in a 1:1 ratio (ALC-Ni2+) accompanied by the color change from red to purple. The detection of histamine is based on high affinity of histamine for Ni2+. The addition of histamine to ALC-Ni2+ caused the complex formation of histamine with Ni2+ in a 1:1 stoichiometry, resulting a hypsochromic shift accompanied by change back of color from purple to red through the release of ALC from ALC-Ni2+. The absorption response is linear with the histamine concentration in the range of 5–150 μM with a detection limit of 7.68 μM. Moreover, other neurotransmitters did not show any significant interference with the histamine detection from the competition experiments. Thus, ALC-Ni2+ can be used as a simple probe for histamine in aqueous solution.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
