Abstract
Prussian blue nanocubes were synthesized via a hydrothermal method. Significantly, the redox couple Ni3+/Ni2+ provided rich oxidation and reduction reactions, which enhance catalytic activity. Furthermore, PBNCs mimic peroxidase activity which could oxidise colourless tetramethyl benzidine (TMB) to a blue colour (TMB+) in the presence of H2O2. Thus, it can be used as a colorimetric sensing platform for detecting cysteine and Cu2+. The addition of cysteine to a TMB + PBNCs sensing system decreases the intensity of the blue colour in the solution with a decrease in the absorption peak at 652 nm in the UV visible spectrum. Subsequently, the addition of Cu2+ into the TMB + PBNCs + Cys sensing system increases the intensity of the blue colour due to complex formation of Cu and cysteine. Therefore, the change in intensity of the blue colour of TMB is directly proportional to the concentration of Cys and Cu2+. As a result, this sensing system is highly sensitive and selective with an effective low detection limit of 0.002 mM for cysteine and 0.0181 mM for Cu2+. Furthermore, this method was applied to the detection of cysteine and copper in spiked real samples and gave satisfactory results.
Highlights
The detection of heavy metal ions in natural aquatic systems is challenging work for contemporary researchers
Different conventional methods have been employed in the detection of copper(II) ions based on atomic absorption spectrometry (AAS)[14,15] inductively coupled plasma aResearch and Department of Chemistry, St
The crystalline structure and phase composition of PBNCs were explained through X-ray diffraction (XRD)
Summary
The detection of heavy metal ions in natural aquatic systems is challenging work for contemporary researchers. Peroxidase-mimicking nanoparticles are highly efficient and superior in properties over natural enzymes in their stability and sturdiness under tough reaction conditions. They are cheap and easy to prepare. Upon addition of Cu2+ to the same solution, it regains the blue colour due to the affinity between a copper ion and the thiol group of cysteine Based on this strategy, a novel colorimetric sensing system was developed for the highly selective and sensitive detection of cysteine and Cu2+. To the best of our knowledge, the effective peroxidase mimicking activity of a PBNC based colorimetric sensing system has been used for the rst time for the detection of cysteine and copper and evaluated with spiked real water samples in aqueous solution
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