Abstract

Blue light-emitting diodes (LEDs) in liquid crystal displays emit high levels of blue light, exposure to which is harmful to the retina. Here, we investigated the protective effects of colored lenses in blue LED light-induced damage to 661W photoreceptor-derived cells. We used eight kinds of colored lenses and one lens that reflects blue light. Moreover, we evaluated the relationship between the protective effects of the lens and the transmittance of lens at 464 nm. Lenses of six colors, except for the SY, PN, and reflective coating lenses, strongly decreased the reduction in cell damage induced by blue LED light exposure. The deep yellow lens showed the most protective effect from all the lenses, but the reflective coating lens and pink lens did not show any effects on photoreceptor-derived cell damage. Moreover, these results were correlated with the lens transmittance of blue LED light (464 nm). These results suggest that lenses of various colors, especially deep yellow lenses, may protect retinal photoreceptor cells from blue LED light in proportion to the transmittance for the wavelength of blue LED and the suppression of reactive oxygen species production and cell damage.

Highlights

  • Blue light-emitting diodes (LEDs) are semiconductor devices that are commonly used as light sources in LED-backlit liquid crystal displays of various electronic appliances such as smartphones, computer screens, and LED lamps

  • Previous in vivo studies have indicated that yellow lenses protect from retinal damage induced by exposure to white or blue LED light.[14,15,16]

  • The current study aimed at investigating the protective effects of colored lenses upon exposure to blue LED light using the previously established model

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Summary

Introduction

Blue light-emitting diodes (LEDs) are semiconductor devices that are commonly used as light sources in LED-backlit liquid crystal displays of various electronic appliances such as smartphones, computer screens, and LED lamps. Blue LEDs display several other properties apart from being a light source. Blue light has been reported to be lethal to insects.[1] blue LED light is shown to display a therapeutic effect in seasonal affective disorder.[2] blue LED emits only short-wavelength high-energy visible light and long-time video display terminal works expose human eyes to blue LED light. A blue light–cutting lens is a yellow lens, which absorbs almost all blue light, or a colorless lens,

Cell Culture
Photoreceptor-Derived Cell Damage Induced by Blue Light-Emitting Diode
Cell Death Analysis by Hoechst 33342 and Propidium Iodide Staining
Cell Viability Assay
Measurement of Reactive Oxygen Species Production
Rate of Cell Death Was Decreased in Several Lens Groups
Several Lens Groups Improved Cell Viability
Reactive Oxygen Species Production Was Decreased in Several Lens Groups
Protective Effect of Lenses Correlated with Transmittance
Discussion
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