Abstract
Objectives. To estimate the survival rate of colorectal cancer (CRC) and determine its predictors among Jordanian patients who were diagnosed in the period of 2005–2010. Methods. This study was based on Jordan cancer registry. All CRC cases that were registered in cancer registry during 2005–2010 were analyzed using the survival analysis. The last date for follow-up was 1st Oct 2016. Results. A total of 3005 patients with CRC were registered during 2005–2010. The overall 5-year and 10-year survival rates for patients with CRC were 58.2% and 51.8%, respectively. The 5-year survival rate decreased significantly from 60.4% for the age <50 years to 49.3% for the age ≥70 years (p < 0.005). The 5-year survival rate was 72.1% for the localized stage, 53.8% for the regional stage, and 22.6% for the distant metastasis. In the multivariate analysis, the only factors that were significantly associated with survival were age, grade, stage, and location of tumor. Conclusions. The overall 5-year and ten-year survival rates for CRC were 58.2% and 51.8%, respectively. Increased age, poor differentiation, advanced cancer stage, and right-sided cancers were associated with lower survival rates. Screening strategies are needed for early detection of colon adenomas and colorectal cancer in Jordan.
Highlights
Colorectal cancer (CRC) is the third most common cancer in men and the second in women according to the latest GLOBOCAN worldwide estimation in 2012 [1]
The total number of patients who were diagnosed with CRC and registered in Jordan cancer registry in the period of 2005–2010 was 3005 patients
Data on the survival analysis of CRC are scant in the Eastern Mediterranean countries including Jordan
Summary
Colorectal cancer (CRC) is the third most common cancer in men and the second in women according to the latest GLOBOCAN worldwide estimation in 2012 [1]. In 2012, CRC was estimated to cause 694,000 deaths (8.5% of total cancer deaths) with more deaths (52%) occurring in the less developed countries [1]. According to the latest comprehensive cancer incidence report in 2012, CRC accounted for 11.3% of all newly diagnosed cases among Jordanians and ranked the second among all cancers in both genders. According to Jordan mortality registry in 2013, neoplasms were the second leading cause of death (16.4% of total deaths), and cancer of small intestine, colon, rectum, and anus accounted for 2% of total deaths [5]
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