Abstract
The influence of temperature and pH on the surface color and total dye content of tablets colored with selected dyes was studied. The representative dyes included were FD&C Red No. 4, Blue No. 1, and Yellow No. 5. Samples of tablets colored with these dyes and buffered at several pH levels were stored at elevated temperatures and tested for both residual dye concentration and fading at their surface. FD&C Red No. 4 was found to be the most stable of the three dyes tested. However, from the results of this study there appears to be no correlation between the fading at the surface of the tablets and the loss in colorant concentration at elevated temperatures.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
