Color Doppler ultrasound in evaluation of post-ocular hemodynamic changes in diabetic patients

Abstract

Objective To evaluate the value of color Doppler ultrasound in the assessment of post-ocular hemodynamic changes in diabetic patients. Methods Sixty patients with type 2 diabetes mellitus (120 eyes) treated at our hospital from January, 2016 to May, 2017 were selected as an observation group and divided into a non-proliferative diabetic retinopathy (NPDR) group, a diabetic no-retinopathy (DNR) group, and a proliferative diabetic retinopathy (PDR) group according to the patients' conditions, 20 cases (40 eyes) for each group. And 60 normal subjects (120 eyes) were set as a control group. All were examined with color Doppler ultrasound. The blood flow parameters of the posterior ciliary artery (PCA), the central retinal artery (CRA), and the ocular artery (OA) of each group were compared. Results The EDV, PSV, and RI of CRA were (5.69 ± 1.23) cm/s, (12.57 ± 2.20) cm/s, and (0.56 ± 0.07) in the control group, were (4.72±1.06)cm/s, (10.33±2.10)cm/s, and (0.63±0.06) in the DNR group, were (3.56±1.04)cm/s, (9.69±1.42)cm/s, and (0.73±0.07) in the NPDR group, and were (2.56±0.89) cm/s, (7.26±1.34)cm/s, and (0.79±0.08) in the PDR group, with statistical differences (P <0.05) The end-diastolic velocity (EDV) and peak systolic velocity (PSV) were the highest in the control group, those in the DNR group came next, and those in the NPDR group, and those in the PDR group; the resistance index (RI) was the lowest in the control group, and second lowest in the DNR group, third in the NPDR group, and fourth in the PDR group; there were statistical differeces (P <0.05). Conclusions Color Doppler ultrasound can dynamically monitor the retinal blood flow status and determine the degree of diabetic retinopathy according to the changes of blood flow and can provide some references for clinical treatment. Key words: Diabetic eye disease; Color Doppler ultrasound; Hemodynamics