Abstract

We tested the hypothesis that altered heat production ability after ovariectomy may be involved in the development of obesity. Two weeks after ovariectomy, food intake of ovariectomized (Ovx) rats was increased and body weight gain was obvious, compared with sham-operated animals. However, colonic temperature of Ovx rats was not different from that of sham-operated animals. Food intake of Ovx rats was similar with that of sham-operated rats at 8 weeks later. In this period, colonic temperature of Ovx rats was not different from that of sham-operated animals and diurnal rhythmicity was maintained. The present data suggested that changes in heat production may be not an important inducer of obesity in both the dynamic and static phases of the development of obesity after ovariectomy.

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