Abstract

Colon metastasis from breast cancer is rare. Gastrointestinal (GI) metastasis is more frequently seen in patients with invasive lobular carcinoma of the breast compared to invasive ductal carcinoma; however, the most common sites of metastasis still remain the lymph nodes, lungs, liver, and bones. We describe a 68-year-old female with a remote history of invasive ductal carcinoma of the breast who presented with abdominal pain and a palpable mass. On imaging, she was found to have a colonic obstruction and underwent a right hemicolectomy that proved to be metastatic invasive ductal carcinoma of the breast.

Highlights

  • Breast cancer is the most commonly diagnosed cancer in women in the United States and is the second most common cause of death in women after lung cancer [1,2,3,4,5,6]

  • Gastrointestinal (GI) metastasis is more frequently seen in patients with invasive lobular carcinoma of the breast compared to invasive ductal carcinoma; the most common sites of metastasis still remain the lymph nodes, lungs, liver, and bones

  • We describe a 68year-old female with a remote history of invasive ductal carcinoma of the breast who presented with abdominal pain and a palpable mass

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Summary

Introduction

Breast cancer is the most commonly diagnosed cancer in women in the United States and is the second most common cause of death in women after lung cancer [1,2,3,4,5,6]. Received 03/14/2018 Review began 05/02/2018 Review ended 05/04/2018 Published 05/07/2018 In this case report, we describe a patient with a history of invasive ductal carcinoma that had metastasized only to bone who presented 15 years later with a colonic obstruction due to a mass. We describe a patient with a history of invasive ductal carcinoma that had metastasized only to bone who presented 15 years later with a colonic obstruction due to a mass It behaved like a primary colon cancer but pathologically was determined to be metastatic invasive ductal carcinoma of the breast. She had a past medical history of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor 2 (HER2)-positive invasive ductal carcinoma of the left breast diagnosed in 1996 She received a modified left radical mastectomy and right simple mastectomy, adjuvant systemic chemotherapy with doxorubicin and cyclophosphamide, radiation to the left chest wall, and was started on Tamoxifen. Given progression of metastatic invasive ductal carcinoma while on letrozole, she was transitioned to exemestane

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