Colonic adenocarcinoma revealing Crohn's disease: a case report

Amal Ankouz,Khalid Ait Taleb,Karim Ibn Majdoub,Khalid Mazaz,Abdelmalek Ousadden

doi:10.1186/1752-1947-4-167

Amal Ankouz, Khalid Ait Taleb + Show 3 more

Open Access

https://doi.org/10.1186/1752-1947-4-167

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Abstract

IntroductionThere is growing evidence from epidemiological studies and clinicopathological data obtained from case reports that Crohn's disease is associated with an increased risk of carcinoma of the large bowel.Case presentationA 70-year-old Arabic African man with undiagnosed Crohn's disease presented with acute abdominal obstruction due to an occlusive carcinoma of the sigmoid. At laparotomy, the colonic tumor was excised with continuity restored by end-to-end anastomosis.ConclusionThe risk of colonic carcinoma in Crohn's disease is increasing. Several case reports actually support the possibility that a genuine association between these two conditions exists.

Highlights

There is growing evidence from epidemiological studies and clinicopathological data obtained from case reports that Crohn's disease is associated with an increased risk of carcinoma of the large bowel.Case presentation: A 70-year-old Arabic African man with undiagnosed Crohn's disease presented with acute abdominal obstruction due to an occlusive carcinoma of the sigmoid
Colorectal cancer occurring in ulcerative colitis was described in 1925 by Crohn [1] but not until 23 years later did Warren and Sommers report the first case of adenocarcinoma complicating regional enteritis [2]
Case report A 70-year-old Arabic African man presented to the emergency department of the University Hospital Hassan II of Fez with a five-day intestinal obstruction with associated abdominal distension and vomiting

Summary

Introduction

Colorectal cancer occurring in ulcerative colitis was described in 1925 by Crohn [1] but not until 23 years later did Warren and Sommers report the first case of adenocarcinoma complicating regional enteritis [2]. Case report A 70-year-old Arabic African man presented to the emergency department of the University Hospital Hassan II of Fez with a five-day intestinal obstruction with associated abdominal distension and vomiting. He gave a history of referred intermittent episodes of constipation for a period of 6 months When examined he was found to have general abdominal tenderness. Postoperative chemotherapy with 5-fluorouracil and folinic acid (5-FU+Folinic acid) was recommended but this was refused by our patient One year later he was still well except for some episodes of diarrhea

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Hamilton SR