COLLOID VERSUS CRYSTALLOID COLOAD FOR THE PREVENTION OF SPINAL ANEASTHESIA INDUCED HYPOTENSION OF ELECTIVE CAESAREAN SECTION

Abstract

Background Spinal anaesthesia is the standard technique for elective caesarean section, but hypotension remains the main complication with this technique. This hypotension has detrimental effects on both mother and foetus. To prevent hypotension, crystalloid or colloid coload with vesopressor may be an alternate choice. Aim To compare the efficacy of crystalloid and colloid coload in presence of phenylephrine infusion for the prevention of spinal anaesthesia induced hypotension. Methods Forty subjects (40) are randomly allocated into two groups. Subjects were infused either crystalloid or colloid within 10 minutes after spinal anaesthesia (coload).Heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), mean blood pressure (MBP) and oxygen saturation were recorded in three minutes interval throughout the surgery. Continuous ECG monitoring was done. Adverse events (nausea, vomiting etc) if any were recorded in case report form (CRF).  Phenylephrine infusion was continued at the rate of 40 mcg/min throughout the surgery. Results Demographic parameters were comparable. HR, SBP, DBP, MBP, Oxygen saturation all are comparable between the groups and within the group in various time period. There was no episode of nausea or vomiting and no requirement of rescue medication of phenylephrine 100 mcg intravenously. Conclusion There is no difference of efficacy of crystalloid and colloid, when use as coload with phenylephrine infusion for the prevention of spinal anaesthesia induced hypotension.  Key words –spinal anaesthesia, crystalloid, colloid, hypotension