Collision Tumor: Dermoid Cysts and Mucinous Cystadenoma in the Same Ovary and a Review of the Literature

Mehmet Sühha Bostanci

doi:10.23937/2377-9004/1410031

Abstract

Collision tumor is defined as the coexistence of two adjacent, but histologically distinct tumors without histological admixture in the same tissue or organ. Collision tumors involving ovaries are extremely rare. The coexistence of a mucinous cystadenoma with a dermoid cyst is infrequently reported. However, the most common histological combination of collision tumor in the ovary is the coexistence of teratoma with mucinous tumors. If a dermoid cyst accompanies a multiseptated cyst and if the multiseptalcyst contains fatty foci, these two components may be associated. Recognizing the potential for the coexistence of these two neoplasms in the same ovary is essential to be able to make a correct diagnosis.

Highlights

Dermoid cyst is a type of germ cell tumor comprising welldifferentiated tissues and three germ cell layers: ectoderm, mesoderm, and endoderm, which is known as mature cystic teratom [1]
Benign mucinous cystadenomas account for 80% of mucinous ovarian tumors and 20-25% of overall benign ovarian tumors [3]
Microscopic examination of the right ovary revealed three tumor types: mucinous cystadenoma corresponded to the wall of the two cysts; mature cystic teratoma produced the skin and subcutaneous tissue, including sebaceous glands and hair containing mass

Summary

Introduction

Dermoid cyst is a type of germ cell tumor comprising welldifferentiated tissues and three germ cell layers: ectoderm, mesoderm, and endoderm, which is known as mature cystic teratom [1]. The juxtaposition with dermoid cysts has been reported as comprising approximately 5% of benign mucinous ovarian tumors and rare examples of proliferating mucinous tumors [7]. The case is here reported of a rare collision tumor in the ovary consisting of mucinous cystadenoma and two distinct dermoid tumors. Microscopic examination of the right ovary revealed three tumor types: mucinous cystadenoma corresponded to the wall of the two cysts; mature cystic teratoma produced the skin and subcutaneous tissue, including sebaceous glands and hair containing mass. Approval for this case report was granted by the Institutional Ethics Committee and informed consent was obtained from the patient (Figures 1-3)

Findings

Discussion

Conclusion