Abstract
The primary cilium is an essential organelle responsible for multiple sensory and signaling activities. Ciliogenesis is achieved by delivery of precursors such as tubulins along the axoneme through intraflagellar transport (IFT), which is mediated by molecular motors and various IFT particles. Distal appendages (DAPs) are known to serve as the recruiting site of IFT proteins. During ciliogenesis, IFT proteins must go through several different zones in cilia. One of missing links of the IFT dynamics is how IFT particles move between the DAPs and the ciliary axoneme.
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