Abstract

The effect of vitrectomy on the course of dry age-related macular degeneration (AMD) in eyes with full-thickness macular holes (FTMHs) is not well understood and has been variably reported in existing studies. The phenomenon of disappearance of confluent soft drusen (drusenoid pigment epithelial detachment [PED]) after macular hole surgery is, however, a rarely reported occurrence. We report a case of a 61-year-old female patient with a large full-thickness macular hole of minimum diameter 586 μm with an underlying drusenoid PED, who underwent a pars plana vitrectomy with inverted internal limiting membrane flap and 20% sulfur hexafluoride gas injection. The macular hole was successfully closed along with collapse of the underlying drusenoid PED during the postoperative follow-up period.

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