Abstract
Collagen VII is the major structural component of the anchoring fibrils that stabilize the cutaneous basement membrane on the dermis. Disruption and, more usually, destruction of the basement membrane are characteristic of wounds that are slow, or fail, to heal, such as chronic lower-limb or pressure ulcers. In this study, the expression of collagen VII was analysed in 28 human chronic cutaneous wounds or scars using a reverse transcription-polymerase chain reaction (RT-PCR) technique. Collagen VII expression was detected in 26 of these 28 cutaneous wounds, but not in two wounds, neither of which showed any clinical evidence of healing.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
