Abstract
Abstract Collagen VII was first isolated from chorioamniotic membranes by limited pepsin digestion and was termed long-chain collagen (LC) before being referred to as collagen VII [911, see 7, 8, 9 for reviews]. Collagen VII is the major structural component of anchoring fibrils [691, 724], the specialized fibrous structures located immediately beneath the lamina densa of many epithelia and which are critical for epidermal-dermal adhesion. Table 12 gives the Swiss Prot database entries for collagen VII.
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