Collagen nano scaffold in tendon repair and its application in the restoration of sports mechanical properties

Abstract

Tendons are specialised dense connective tissue, which connect bone cartilage and muscle tissue, and play a role in transmitting the tension, movement and stabilising joints produced by muscles. Tendon injury is a common clinical disease, the repair of tendon injury has both exogenous and endogenous healing. Exogenous repair is involved in early repair, which mainly depends on cells infiltrated from external tissues, including synovium. This repair mechanism can lead to the adhesion of tendon and surrounding tissue to form paralysis marks, and damage the activity of muscle and leg, prevention of adhesion is an important link in the treatment of muscle and leg injury. In this paper, the main diaphragm mechanism of collagen scaffolds is used to reduce the participation of exogenous repair, prevent the formation of muscle leg adhesion, and selectively guide the attachment and proliferation of endogenous tendon cells to the damaged site, so as to achieve the purpose of tendon tissue injury repair, to provide a new idea and method for the prevention and treatment of tendon adhesion and injury repair in clinical work.