Abstract
To the Editors: We read with great interest the article recently published in the European Respiratory Journal ( ERJ ) by Rios et al. 1 regarding ventilator-associated pneumonia (VAP) due to colistin susceptible-only microorganisms. The authors concluded that colistin could be a suitable antibiotic for the initial empiric antimicrobial therapy in their intensive care unit (ICU) since they identified 30 carbapenem-sensitive (Carb-S) and 31 colistin-sensitive (Col-S) isolates. In our seven-bed general ICU 184 patients were admitted during a period of 18 months with the following characteristics: 125 (67.9%) males; age (mean±sd) 57.8±22.7 yrs; Simplified Acute Physiology Score II 48.2±11.8; Acute Physiology and Chronic Health Evaluation II 19.1±5.7; mean ICU stay 36.7±36.9 days; mean mechanical ventilation duration 29.2±15.9 days; and a total of 3,262 ventilator days. A total of 52 (28.3%) VAP episodes (15.9 episodes per 1,000 ventilator days, with a mean clinical pulmonary infection score at VAP onset of 7.4±1.6) …
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