Abstract

Epidemiological data, clinical observation and animal experiments have shown that cold wave is closely associated with the onset of stroke. When a population with stroke etiology or risk factors is under pre-stroke state, they will have stroke under the influence of various inducing factors. Cold wave is the external factor that causes the body to enter the pre-stroke state and there are many possible mechanisms. The drug intervention of stroke-prone hypertensive rats at 1 week before the cold wave can reduce the occurrence of stroke during cold wave, suggesting that it is of great significance to conduct preventive intervention to the pre-stroke population before the cold wave coming. Key words: Stroke; Brain Ischemia; Cerebral Hemorrhage; Subarachnoid Hemorrhage; Cold Temperature

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