Colchicine Intoxication In A Patient With Unilateral Renal Agenesis

Abstract

Colchicine is an alkaloid used in the treatment of acute gout attacks, Familial Mediterranean Fever, Behçet's Disease and inflammatory bowel diseases. Depending on the dose taken, the clinic occurs in various ways. Gastrointestinal manifestations are common in colchicine intoxication, but multi-organ failure is a more rare and more serious problem. As the blood level of colchicine is determined by the kidney and the liver, toxicity may progress more rapidly in dysfunction of these organs. In this case report, we aimed to remind that colchicine intoxications may be more mortal in patients with renal insufficiency.