Abstract
Acquired reactive perforating collagenosis is a perforating dermatosis characterized by transepidermal elimination of collagen. It is frequently associated to diabetes mellitus and chronic renal insufficiency, but it is also related to other systemic diseases. The lesions tend to resolve once the underlying condition is treated. We report two patients with the condition. A 65 year-old diabetic female on hemodialysis consulted for multiple itching cutaneous ulcers lasting one year. On physical examination, hyperpigmented papules and nodules were observed. A 65 year-old female with chronic renal failure in hemodialysis consulted for itching lesions in hands, forearms and arms. On physical examination, hyperpigmented lesions with ulcers, erosions and crusts were observed. In both cases, the pathological study of the lesions disclosed a reactive perforating collagenosis.
Highlights
Acquired reactive perforating collagenosis is a perforating dermatosis characterized by transepidermal elimination of collagen
Este término engloba un amplio espectro de desórdenes perforantes de la piel que se presentan en asociación a enfermedades sistémicas[3]
En el contexto de la insuficiencia renal crónica el diagnóstico diferencial debe incluir patologías relacionadas al prurito urémico como otras dermatosis perforantes adquirida, liquen plano, prurigo nodularis, porfiria, pseudoporfiria, calcifilaxis, y dermatosis bulosa por IgA19
Summary
Acquired reactive perforating collagenosis is a perforating dermatosis characterized by transepidermal elimination of collagen. En las últimas décadas se han descrito varios casos con aparición en la vida adulta en pacientes con diversas enfermedades como la diabetes mellitus y la insuficiencia renal crónica, por lo que se acuñó un nuevo término: dermatosis perforante adquirida.
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