Abstract
Hemoglobin D [Hb D] is the second most common hemoglobin variant in South west of Iran. It places in second position after hemoglobin S. So far up to present, from the genetic point of view, all cases of Hb D are hemoglobin Punjab. Hb D, in all forms, heterozygote, homozygote and compound heterozygote presents with mild anemia or completely asymptomatic that may be discovered accidentally. There was a case presentation of a child with genotype of Hb D/β0 thalassemia co-inherited with ααα anti 3.7 triplication and phenotype of moderate to severe anemia similar to thalassemia intermediate. Key words: Hb D-Punjab, ααα anti 3.7 triplication, South west of Iran.
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