Coincident iridocorneal endothelial syndrome and keratoconus

Abstract

This report describes a rare case coincident keratoconus and Iridocorneal Endothelial (ICE) syndrome in a 43-year-old male with atopy who presented with progressively declining vision. A beaten silver appearance of the right endothelium with a dark-light reversal pattern and endothelial pleomorphism was consistent with the Chandler's syndrome variant of ICE. Keratoconus was demonstrated by irregular astigmatism with thinning and steepening on corneal tomography. He remained stable throughout 14 years with no evidence of secondary glaucoma or progression in keratoconus with conservative management. Coincident ICE and keratoconus is a rare entity with only one other published case of the Chandler's syndrome variant.