Abstract

Cohort Profile: The UK Women’s Cohort Study (UKWCS) Janet E Cade,* Victoria J Burley, Nisreen A Alwan, Jayne Hutchinson, Neil Hancock, Michelle A Morris, Diane E Threapleton and Darren C Greenwood School of Food Science and Nutrition, Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK, Department of Health Sciences, University of York, York, UK, School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong, Academic Unit of Primary Care and Population Sciences, Faculty of Medicine, University of Southampton, Southampton, UK and School of Geography, University of Leeds, Leeds, UK

Highlights

  • An inverse association for risk of breast cancer with total fibre and cereal fibre intake has been demonstrated in premenopausal, but not postmenopausal women.[9]

  • The top quintile of fibre intake was associated with a hazard ratio of 0.48 compared with the lowest quintile

  • An exploration of dietary acrylamide intake in relation to breast cancer risk in the cohort found no evidence of association

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Summary

Cohort Profile

Janet E Cade,1* Victoria J Burley,[1] Nisreen A Alwan,[1,5] Jayne Hutchinson,[1,3] Neil Hancock,[1] Michelle A Morris,[1,6] Diane E Threapleton[4] and Darren C Greenwood[2]

Why was the cohort set up?
Who is in the cohort?
How often have the participants been followed up?
South West
Cohort consortia and other work including UKWCS
Exposure measurements
Outcome measurement
Diet and breast cancer outcomes
Cognitive function
Diet and cardiovascular disease outcomes
Other health and lifestyle outcomes related to diet
Risk factor
What are the main strengths and weaknesses?

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