Abstract

Objective: Although most studies investigating sudden gains in treatments for posttraumatic stress disorder (PTSD) report a positive association between sudden gains and outcomes at the end of treatment, less is known about sudden gains in routine clinical care and the processes involved in their occurrence. This study investigated changes in cognitive factors (negative appraisals, trauma memory characteristics) before, during, and after sudden gains in PTSD symptom severity. Method: Two samples (N1 = 248, N2 = 234) of patients who received trauma-focused cognitive therapy for PTSD in routine clinical care were analyzed. Mahalanobis distance matching, including the propensity score, was used to compare patients with sudden gains and similar patients without sudden gains. Estimates from both samples were meta-analyzed to obtain pooled effects. Results: Patients with sudden gains (n1 = 76, n2 = 87) reported better treatment outcomes in PTSD symptom severity, depression, and anxiety at the end of therapy and follow-up than those without sudden gains. No baseline predictors of sudden gains could be reliably identified. During sudden gains, those with sudden gains had greater changes in both cognitive factors than matched patients. Meta-analyses of the two samples showed that negative appraisals had already decreased in the session prior to sudden gains compared with matched patients. Conclusions: The pooled estimates suggest that changes in negative trauma-related appraisals precede sudden gains in PTSD symptoms. The results suggest that interventions that promote change in appraisals may also facilitate sudden gains in therapy.

Highlights

  • Cognitive Processes Associated With Sudden Gains in Cognitive Therapy for Posttraumatic Stress Disorder in Routine Care

  • The present study investigated sudden gains in two large clinical samples of patients with posttraumatic stress disorder (PTSD) treated with Cognitive therapy for PTSD (CT-PTSD) in routine clinical care, using the same criteria and including a matched control group

  • This study showed, in two independent, consecutive samples, that sudden gains occur in about a third of patients treated with CT-PTSD and reliably predict better treatment outcomes

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Summary

Methods

This study is a secondary analysis of data drawn from studies investigating the effectiveness of CT-PTSD in routine clinical care. Two cohorts of consecutive patients with PTSD treated in a specialist outpatient clinic for anxiety disorders serving an innercity population characterized by above-average rates of social deprivation and crime and a greater proportion of ethnic minorities than the national average were treated with CT-PTSD. Patients met the criteria for PTSD according to the Structured Clinical Interview for DSM-IV (SCID; First, Gibbon, Spitzer, Williams, & Benjamin, 1997), and PTSD was their main problem. The SCID was administered by trained clinical psychologists. Outcome measures (pretreatment and last-session symptom scores) were available for all patients, including dropouts (14% and 16% respectively), and results are reported by Ehlers et al (2013) for Sample 1 (N ϭ 330) and by Ehlers et al (2020) for Sample 2 (N ϭ 343), see Appendix for data transparency statement. Ethical approval was granted by the local research ethics committee

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