Cognitive performance and perceived cognitive function in multiple myeloma patients treated with an autologous stem cell transplant: Results of the Brilliant Study

Abstract

Treatment of multiple myeloma (MM) with induction chemotherapy followed by autologous hematopoietic cell transplant (auto HCT) improves event-free survival and overall survival. This prolonged survival has unmasked long-term complications related to therapy that impact quality of life. Studies in other cancers have identified cognitive impairment related to chemotherapy treatment based on exposure or dose. To date, there are no studies evaluating the impact auto HCT may have on cognition in MM patients.